Salvation cannot be “lost,” but it can be given up. A person can decide to disobey God after having prayed a prayer of repentance at one time. However, the Holy Spirit will chastise and convict the wayward soul to the point that the person must be very determined to not yield to God in order to put aside salvation and spend eternity without God in Hell. A person can numb his mind to the promptings of the Holy Spirit – making himself unable to feel the tug towards God (Romans 1:28). This is a sad situation and Christians must be quick to heed God’s call in order to keep their conscience clean and open before God.